Kalsec expanded our research collaboration with Codexis, Inc., a leading enzyme engineering company enabling the promise of synthetic biology, by entering into an exclusive supply agreement for a novel enzyme to sustainably produce Kalsec’s newest generation of natural hop acid.

Novel Natural Hop Acids

Codexis’ latest novel performance enzyme product, developed in close collaboration with Kalsec’s innovation team, will enable natural, biocatalytic production of new, advanced hop products. Using Codexis’ CodeEvolver® technology platform, the new enzyme was developed for improved functionality, stability and efficiency, delivering consistent hop characteristics and taste that offer unique advantages for final beverage products. The enzyme is expected to enable commercial-scale production of Kalsec’s newest natural hop acid by early 2022.

“We are delighted to grow our collaboration with Kalsec to include the commercialization of this novel enzyme for their hop extracts business, as well as the development of additional new enzyme products,” said John Nicols, President and Chief Executive Officer of Codexis. “Our CodeEvolver® platform is unrivaled in its ability to discover and design ideal, high performance enzymes that enable our partners to dramatically reduce the cost and increase the sustainability of manufacturing their products. Leveraging this engineering prowess to support innovative, sustainable and clean-label products for our food and beverage ingredients customers is core to our mission of creating enzymes that make a difference, for the health of people and the planet.”

Advanced Hop Products

“Kalsec is a pioneer in the development of advanced hop products, and we continually seek innovative solutions to deliver value to our customers and the end consumer,” said Scott Nykaza, Chief Executive Officer of Kalsec. “This unique enzyme will enable the product differentiation and benefits our customers need to meet the market demand for high performing hop products. We are very excited to expand our partnership with Codexis to drive innovation through new, sustainable bioprocesses that capture the best that nature has to offer.”

Kalsec’s advanced hop products include HopRival® natural hop extracts, kettle aroma extracts, hop acids, high purity hop oils, specialized hop flavorings and customized blends that provide sensory differentiators and brewing advantages to the global brewing industry.

About Codexis

Codexis is a leading enzyme engineering company leveraging its proprietary CodeEvolver® platform to discover and develop novel, high performance enzymes and novel biotherapeutics. Codexis enzymes have applications in the sustainable manufacturing of pharmaceuticals, food, and industrial products; in the creation of the next generation of life science tools; and as gene therapy and biologic therapeutics. The Company’s unique performance enzymes drive improvements such as: reduced energy usage, waste generation and capital requirements; higher yields; higher fidelity diagnostics; and more efficacious therapeutics. Codexis enzymes enable the promise of synthetic biology to improve the health of people and the planet. For more information, visit www.codexis.com.

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